一、临床资料患者,男性,44岁,空客A320机长,总飞行时间13000 h.2006年始心电图运动负荷试验(treadmill exercise test,TET)可疑阳性(Ⅱ、Ⅲ、aVF、V4～V6水平下移0.1 mV);门控核素心肌灌注显像(single-photon emission computed tomography,SPECT)正常,评定为合格.

一、临床资料患者男性,年龄53岁,民航波音747-400驾驶员,飞行时间22 500 h.1998年12月7日在年度体检时首次发现次极量运动试验可疑阳性,平板运动试验3 min即现ST-TⅡ、Ⅲ、aVF V2～V6↓0.1～0.2 mV,运动后3 min回到基线.

Objective　To study the efficacy and safety of cutting balloons in coronary interventions.Methods　Twenty-two patients with 23 narrowed coronary arteries and 25 lesions enrolled the study, 17 of whom had 18 diseased coronary arteries and 18 lesions were in-stent restenosis. The average time from previous stenting was 7.60±3.53 months. The lesions were dilated with cutting balloons. Results　All of the lesions were dilated successfully by 5.16±2.30 inflations of a cutting balloon. The mean total duration of balloon inflation was 233.96±94.83 seconds at pressures up to 9.40±1.96 bars. The severity of vascular stenosis was lessened substantially (89.64±8.65% vs 17.60±17.15%， P=0.000) without severe complications. Three restenotic lesions were further dilated with conventional balloons, another one was stented again because of a dissection distal to the previous stent. Three primary lesions were stented for dissection or residual stenosis. Angina pectoris reoccurred in two patients in a mean follow-up period of 7.42±6.87 (range 0.5-20) months. Conclusion　Cutting balloon dilation is an effective and safe choice in interventions for coronary disease especially for in-stent restenosis.