The Background of the Asian and Pacific Decade of Persons with DisabilitiesThe Asia and Pacific RegionAsia and Pacific is a vast region.It has about 60％of the world population.In Asia,you can find some of the oldest civilizations and religions;some of the most advanced as well as poorest economies,and many Asians living in rural and mountainous areas.Diversities and differences among governments and peoples of Asia are the norm rather than the exception.Poverty situation of people with disabilities in Asia:People with disabilities in the region are facing critical and severe situations.About 80％ of Asian people with disabilities live in rural or remote areas.Among the 900million very poor people in the Region,the disabled are among the most discriminated against and the most impoverished.
金标法即滴金免疫测定法(DIGFA)检测日本血吸虫抗体已在许多血吸虫病流行区用于疫情监测[1-3].为观察DIGFA在云南血吸虫病不同类型流行区的现场应用价值,我们比较了分别由浙江省医学科学院寄生虫病研究所和深圳康百得生物科技公司生产的血吸虫抗体DIGFA试剂盒的检测结果,现报告如下.
Analyse the genetic and antigenic variant of rabies virus in Guangxi with epidemiological method, monoclonal antibodies reaction pattern and molecular biological technique. Rabies incidence has increase in recent three years in Guangxi, especially in mountainous areas. Investigation into the human rabies found that there are about 20％ vaccinated defeat cases.On the basis of their reactivity to monoclonal antibodies against the viral nucleocapsid protein(mAb-N),4 street strains isolated from different areas where enzootic rabies is shown had different reaction patterns compared with Chinese vaccine strain(3aG). The nucleotide and amino acid sequence of street strain(GX89_1) G and N gene were compared with 3aG, the overall nucleotide homology of GX89_1 with 3aG was 84.5％ and amino acid homology of GX89_1 with 3aG was 89.5％ in G gene.The overall nucleotide homology of GX89_1 with 3aG was 86％ in N gene and they were not in the same group.There are several amino acid replacement in AA 243_268 of G protein that can affect the antigenicity of rabies virus.The findings suggest that there are different street strains of rabies virus in Guangxi.
