1 GENERAL DATA Case condition:Famle,aged 35 years old,craninal bone repair was performed on May 1998.deficiency of cranial 5 cm× 5 cm,region:tempora and parietal area.Operative time:type of operation is II type repair,repair material was fixed with double size 7 silk,and moulded under local intensified anesthesin.Wound were duched with gentamycin sulfate liquid,drain was laid,removed on next day.Secondary operation:Result of exploration(leading to pain):subcutaneous hydrops.

正确理解骨形成蛋白(Bone Morphogenetic Protein,BMP)在骨缺损修复中的矛盾与克服,将有助于BMP的研究、应用和骨缺损修复这一临床难题的解决.

Bone is a highly vascularized tissue, although this aspect of bone is often overlooked. In this article, the importance of blood flow in bone repair and regeneration will be reviewed. First, the skeletal vascular anato-my, with an emphasis on long bones, the distinct mechanisms for vascularizing bone tissue, and methods for remodeling existing vasculature are discussed. Next, techniques for quantifying bone blood flow are briefly summarized. Finally, the body of experimental work that demonstrates the role of bone blood flow in fracture healing, distraction osteogenesis, osteoporosis, disuse osteopenia, and bone grafting is examined. These results illustrate that adequate bone blood flow is an important clinical consideration, particularly during bone regeneration and in at-risk patient groups.