JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The Journal of Steroid Biochemistry and Molecular Biology is devoted to new experimental or theoretical developments in areas related to steroids. It publishes original papers as well as general and mini-reviews, proceedings of selected meetings and rapid communications (brief highly-topical articles of particular interest).The journal covers a wide range of topics relating to steroids:- Molecular, cellular, and physiological actions of steroid hormones, steroid anti-hormones and their analogs via regulation of gene expression or other mechanisms. Structure, function, regulation, and cell biology of receptors of the steroid-thyroid-retinoid superfamily. Cross-talk between steroids, steroid receptors and other signal transduction pathways. Steroids and cell proliferation, regulation of cell cycle genes. Steroid transport. Steroids and cancer: functional relationships in normal and neoplastic tissues between steroid hormones and cytokines, growth factors, growth inhibitors, and oncogenes. Steroids and cancer prevention. Biosynthesis, secretion, and metabolism of steroids and of biologically-related compounds, and their regulation by peptide hormones, prostaglandins and other substances. Molecular aspects of enzymes involved in steroidogenesis. Novel therapeutic applications of new steroid agonists or antagonists. Steroids and neuroendocrinology or neuroimmunology. Neurosteroids, steroid action on synactic transmission and modulation. Steroid hormones and hypertension. Steroids and their actions on bone and on the cardiovascular systems. Steroid enzyme inhibitors. Steroids and analogs in menopause. Steroids in hormone replacement therapy. Steroid hormones in osteoporosis: basic and clinical applications. Steroids and contraception. Defects in steroid metabolism. Steroid hormones during pregnancy, development and sex differentiation. Structure, physicochemical, chemical and pharmacological characteristics of natural and synthetic steroids and related compounds of biological interest. Innovative techniques relating to steroids and biologically-related substances. Clinical and physiological studies of inborn or acquired changes of biosynthesis, metabolism or action of steroids and their receptors. Comparative endocrinology and evolution of steroids. Environmental effects on steroid metabolism and action.